ΔE 19.6, loose: different enough that you should pick on purpose. Royal Blue is a little lighter, much more saturated, cooler than Indigo.
Not as a straight swap; see the closer alternatives below. Loose match (ΔE 20). Royal Blue is a little lighter, much more saturated, cooler than Indigo.
The same difference applies the other way round: Indigo is a little darker, much more muted, warmer.
ΔE is the colour difference between our two swatch estimates: under about 6 is close, over about 15 is loose. Real paints also differ in finish, coverage and how they thin, so test before you commit.
See Indigo on the colour wheel See Royal Blue on the colour wheel
All matches: Indigo equivalents · Royal Blue equivalents