ΔE 16.1, loose: different enough that you should pick on purpose. Hydra Turquoise is a little lighter, more muted, warmer than Neptunus Blue.
Not as a straight swap; see the closer alternatives below. Loose match (ΔE 16). Hydra Turquoise is a little lighter, more muted, warmer than Neptunus Blue.
The same difference applies the other way round: Neptunus Blue is a little darker, more saturated, cooler.
ΔE is the colour difference between our two swatch estimates: under about 6 is close, over about 15 is loose. Real paints also differ in finish, coverage and how they thin, so test before you commit.
See Neptunus Blue on the colour wheel See Hydra Turquoise on the colour wheel
All matches: Neptunus Blue equivalents · Hydra Turquoise equivalents