ΔE 21.2, loose: different enough that you should pick on purpose. Fluorescent Red is a little darker, cooler than Fluor Orange.
Not as a straight swap; see the closer alternatives below. Loose match (ΔE 21). Fluorescent Red is a little darker, cooler than Fluor Orange.
The same difference applies the other way round: Fluor Orange is a little lighter, warmer.
ΔE is the colour difference between our two swatch estimates: under about 6 is close, over about 15 is loose. Real paints also differ in finish, coverage and how they thin, so test before you commit.
See Fluor Orange on the colour wheel See Fluorescent Red on the colour wheel
All matches: Fluor Orange equivalents · Fluorescent Red equivalents