Heartfire vs Scrofulous Brown

How close are they?

ΔE 16.9, loose: different enough that you should pick on purpose. Scrofulous Brown is noticeably darker, warmer than Heartfire.

Can I use Scrofulous Brown instead of Heartfire?

Not as a straight swap; see the closer alternatives below. Loose match (ΔE 17). Scrofulous Brown is noticeably darker, warmer than Heartfire.

Can I use Heartfire instead of Scrofulous Brown?

The same difference applies the other way round: Heartfire is noticeably lighter, cooler.

ΔE is the colour difference between our two swatch estimates: under about 6 is close, over about 15 is loose. Real paints also differ in finish, coverage and how they thin, so test before you commit.