ΔE 15.6, loose: different enough that you should pick on purpose. Primer Red Oxide is a little darker, much more muted than Spiritstone Red.
Not as a straight swap; see the closer alternatives below. Loose match (ΔE 16). Primer Red Oxide is a little darker, much more muted than Spiritstone Red.
The same difference applies the other way round: Spiritstone Red is a little lighter, much more saturated.
ΔE is the colour difference between our two swatch estimates: under about 6 is close, over about 15 is loose. Real paints also differ in finish, coverage and how they thin, so test before you commit.
See Spiritstone Red on the colour wheel See Primer Red Oxide on the colour wheel
All matches: Spiritstone Red equivalents · Primer Red Oxide equivalents