ΔE 15.5, loose: different enough that you should pick on purpose. Sky Blue is noticeably lighter, more saturated than Lothern Blue.
Not as a straight swap; see the closer alternatives below. Loose match (ΔE 15). Sky Blue is noticeably lighter, more saturated than Lothern Blue.
The same difference applies the other way round: Lothern Blue is noticeably darker, more muted.
ΔE is the colour difference between our two swatch estimates: under about 6 is close, over about 15 is loose. Real paints also differ in finish, coverage and how they thin, so test before you commit.
See Lothern Blue on the colour wheel See Sky Blue on the colour wheel
All matches: Lothern Blue equivalents · Sky Blue equivalents