ΔE 34.7, loose: different enough that you should pick on purpose. Hexos Palesun is much more muted than Screaming Sun.
Can I use Hexos Palesun instead of Screaming Sun?
Not as a straight swap; see the closer alternatives below. Loose match (ΔE 35). Hexos Palesun is much more muted than Screaming Sun.
Can I use Screaming Sun instead of Hexos Palesun?
The same difference applies the other way round: Screaming Sun is much more saturated.
ΔE is the colour difference between our two swatch estimates: under about 6 is close, over about 15 is loose. Real paints also differ in finish, coverage and how they thin, so test before you commit.