ΔE 17.6, loose: different enough that you should pick on purpose. Mediterranean Blue is noticeably lighter, more saturated, cooler than Ultramarine Blue.
Not as a straight swap; see the closer alternatives below. Loose match (ΔE 18). Mediterranean Blue is noticeably lighter, more saturated, cooler than Ultramarine Blue.
The same difference applies the other way round: Ultramarine Blue is noticeably darker, more muted, warmer.
ΔE is the colour difference between our two swatch estimates: under about 6 is close, over about 15 is loose. Real paints also differ in finish, coverage and how they thin, so test before you commit.
See Ultramarine Blue on the colour wheel See Mediterranean Blue on the colour wheel
All matches: Ultramarine Blue equivalents · Mediterranean Blue equivalents