ΔE 17.3, loose: different enough that you should pick on purpose. Primary Cyan is a little lighter, much more saturated, warmer than Royal Blue.
Not as a straight swap; see the closer alternatives below. Loose match (ΔE 17). Primary Cyan is a little lighter, much more saturated, warmer than Royal Blue.
The same difference applies the other way round: Royal Blue is a little darker, much more muted, cooler.
ΔE is the colour difference between our two swatch estimates: under about 6 is close, over about 15 is loose. Real paints also differ in finish, coverage and how they thin, so test before you commit.
See Royal Blue on the colour wheel See Primary Cyan on the colour wheel
All matches: Royal Blue equivalents · Primary Cyan equivalents