ΔE 10.5, fair: the same colour family, but not a straight swap. Medium Flesh is a little lighter, cooler than Rust.
Only where an exact match doesn’t matter, such as a new unit or a highlight. Fair match (ΔE 10). Medium Flesh is a little lighter, cooler than Rust.
The same difference applies the other way round: Rust is a little darker, warmer.
ΔE is the colour difference between our two swatch estimates: under about 6 is close, over about 15 is loose. Real paints also differ in finish, coverage and how they thin, so test before you commit.
See Rust on the colour wheel See Medium Flesh on the colour wheel
All matches: Rust equivalents · Medium Flesh equivalents