ΔE 13.7, fair: the same colour family, but not a straight swap. Deep Sky Blue is noticeably lighter, more muted than Mediterranean Blue.
Only where an exact match doesn’t matter, such as a new unit or a highlight. Fair match (ΔE 14). Deep Sky Blue is noticeably lighter, more muted than Mediterranean Blue.
The same difference applies the other way round: Mediterranean Blue is noticeably darker, more saturated.
ΔE is the colour difference between our two swatch estimates: under about 6 is close, over about 15 is loose. Real paints also differ in finish, coverage and how they thin, so test before you commit.
See Mediterranean Blue on the colour wheel See Deep Sky Blue on the colour wheel
All matches: Mediterranean Blue equivalents · Deep Sky Blue equivalents