ΔE 11.2, fair: the same colour family, but not a straight swap. Safety Orange is a little lighter, more saturated than Flame Orange.
Only where an exact match doesn’t matter, such as a new unit or a highlight. Fair match (ΔE 11). Safety Orange is a little lighter, more saturated than Flame Orange.
The same difference applies the other way round: Flame Orange is a little darker, more muted.
ΔE is the colour difference between our two swatch estimates: under about 6 is close, over about 15 is loose. Real paints also differ in finish, coverage and how they thin, so test before you commit.
See Flame Orange on the colour wheel See Safety Orange on the colour wheel
All matches: Flame Orange equivalents · Safety Orange equivalents