ΔE 15.9, loose: different enough that you should pick on purpose. Angron Red Clear is much more saturated, cooler than Medium Rust.
Not as a straight swap; see the closer alternatives below. Loose match (ΔE 16). Angron Red Clear is much more saturated, cooler than Medium Rust.
The same difference applies the other way round: Medium Rust is much more muted, warmer.
ΔE is the colour difference between our two swatch estimates: under about 6 is close, over about 15 is loose. Real paints also differ in finish, coverage and how they thin, so test before you commit.
See Medium Rust on the colour wheel See Angron Red Clear on the colour wheel
All matches: Medium Rust equivalents · Angron Red Clear equivalents