ΔE 11.5, fair: the same colour family, but not a straight swap. Squig Orange is a little darker, more muted than Medium Orange.
Only where an exact match doesn’t matter, such as a new unit or a highlight. Fair match (ΔE 12). Squig Orange is a little darker, more muted than Medium Orange.
The same difference applies the other way round: Medium Orange is a little lighter, more saturated.
ΔE is the colour difference between our two swatch estimates: under about 6 is close, over about 15 is loose. Real paints also differ in finish, coverage and how they thin, so test before you commit.
See Medium Orange on the colour wheel See Squig Orange on the colour wheel
All matches: Medium Orange equivalents · Squig Orange equivalents